Medical marijuana (MM) is widespread in lots of medical fields, together with oncology, with restricted use in pediatric oncology the place analysis is scarce and infrequently exhibits conflicting outcomes. This analysis focuses on assuaging uncomfortable side effects of anticancer therapy as an integral a part of supportive and palliative care of kids with most cancers. We report our expertise with MM therapy in 50 youngsters, adolescents, and younger adults with various kinds of most cancers throughout 2010-2017. The primary indications for prescriptions have been nausea and vomiting, decreased temper, disturbed sleep, and ache. The remedy was provided to 30 sufferers through oil drops (60%) and 11 through smoking (22%), adopted by vaporization, capsules, or mixtures of assorted routes. Optimistic results have been reported by verbal youngsters and fogeys in 80% of circumstances. MM was usually properly tolerated with few sufferers reporting toxicity, with the most typical hostile reactions being burning within the throat and anxiousness assaults in topics who selected to smoke the product. We conclude that MM could function a probably helpful complementary remedy to standard supportive therapy of kids affected by most cancers on the finish of life. Additional analysis is required on the security and efficacy and the implications of extended use in pediatric populations.

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Ofir R1, Bar-Sela G2, Weyl Ben-Arush M1, Postovsky S1.